Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.
نویسندگان
چکیده
There is no FDA-approved vaccine for the potent plant toxin ricin. We have developed a recombinant ricin vaccine, RiVax. Without adjuvant it is safe and immunogenic in mice, rabbits, and humans. Based on our studies in mice, we now report the results of a small clinical trial with Alhydrogel-adsorbed RiVax.
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ورودعنوان ژورنال:
- Clinical and vaccine immunology : CVI
دوره 19 10 شماره
صفحات -
تاریخ انتشار 2012